This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SCGB1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the Central region of human SCGB1D2.
anticorps LIPB, anticorps LPHB, anticorps LPNB, anticorps Pbpc1bs, anticorps Psbpc1, anticorps secretoglobin family 1D member 2, anticorps secretoglobin, family 1D, member 2, anticorps SCGB1D2, anticorps Scgb1d2
Sujet
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.