IL2RG anticorps

N° du produit ABIN6579821

Détail du produit anti-IL2RG anticorps

Antigène: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivité: Humain, Chien

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL2RG est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.

Réactivité croisée (Details): Human, Canine (Dog)

Purification: Purified by protein-G affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human CD132-transfected cell line

Clone: TUGh4

Isotype: IgG2b kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur IL2RG

Antigène: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Autre désignation: CD132 (IL2RG Produits)

Synonymes: anticorps Ab2-183, anticorps Cd132, anticorps CD132, anticorps CIDX, anticorps IL-2RG, anticorps IMD4, anticorps P64, anticorps SCIDX, anticorps SCIDX1, anticorps [g]c, anticorps gamma(c), anticorps gc, anticorps interleukin 2 receptor subunit gamma, anticorps interleukin 2 receptor subunit gamma L homeolog, anticorps interleukin 2 receptor, gamma chain, anticorps IL2RG, anticorps il2rg.L, anticorps Il2rg

Sujet: Interleukin 2 receptor subunit gamma,CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.,common gamma chain, IL2RG, SCIDX, IMD4

ID gène: 3561

UniProt: P31785

Pathways: Signalistation JAK/STAT, Growth Factor Binding