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DYRK2 anticorps (C-Term)

DYRK2 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB34467 unconjugated
N° du produit ABIN657991
  • Antigène Voir toutes DYRK2 Anticorps
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Épitope
    • 15
    • 10
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 521-549, C-Term
    Reactivité
    • 42
    • 31
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 55
    • 7
    • 1
    Lapin
    Clonalité
    • 56
    • 7
    Polyclonal
    Conjugué
    • 26
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DYRK2 est non-conjugé
    Application
    • 56
    • 33
    • 27
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.
    Clone
    RB34467
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DYRK2 Anticorps primaire
  • Indications d'application
    WB: 1:2000. WB: 1:1000. WB: 1:8000. IHC-P: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Mouse Dyrk2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Date de péremption
    6 months
  • Antigène
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Autre désignation
    Dyrk2 (DYRK2 Produits)
    Synonymes
    anticorps DYRK2, anticorps fc18c09, anticorps si:ch211-266a5.8, anticorps wu:fa09g03, anticorps wu:fc18c09, anticorps 1810038L18Rik, anticorps dual specificity tyrosine phosphorylation regulated kinase 2, anticorps dual specificity tyrosine-phosphorylation-regulated kinase 2, anticorps dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2, anticorps DYRK2, anticorps CpipJ_CPIJ014802, anticorps dyrk2, anticorps Dyrk2
    Sujet
    Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
    Poids moléculaire
    66556
    ID gène
    69181
    NCBI Accession
    NP_001014412
    UniProt
    Q5U4C9
    Pathways
    Regulation of Carbohydrate Metabolic Process
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