MMP2 anticorps

N° du produit ABIN659015

Détail du produit anti-MMP2 anticorps

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This MMP2 antibody is generated from mouse immunized with MMP2 recombinant protein.

Clone: 6E3F8

Isotype: IgG2b kappa

Information d'application

Indications d'application: WB: 1:200~1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MMP2 (ABIN659015)

Zhou, Wang, Ban, Zeng, Zhu, Li, Guan, Li: "DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma." dans: Oncogene, Vol. 37, Issue 8, pp. 1086-1094, (2018) (PubMed).

Li, Zhou, Yang, Zhou, Tan, Yuan, Song, Chen, Zhang: "The CD147/MMP-2 signaling pathway may regulate early stage cardiac remodelling in spontaneously hypertensive rats." dans: Clinical and experimental pharmacology & physiology, Vol. 43, Issue 11, pp. 1125-1133, (2017) (PubMed).

Huang, Chiu, Chou, Su, Chen, Chai, Huang, Huang, Yuan, Lee: "Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax." dans: The Kaohsiung journal of medical sciences, Vol. 33, Issue 1, pp. 17-23, (2017) (PubMed).

Wang, Cao, Huang, Ke, Luo, Lin, Wang, Zhang, Wang: "EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway." dans: Oncotarget, Vol. 6, Issue 16, pp. 14191-208, (2016) (PubMed).

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2 (MMP2 Produits)

Synonymes: anticorps 2-MMP, anticorps CG1794, anticorps DM2-MMP, anticorps Dm2-MMP, anticorps Dmel\\CG1794, anticorps MMP2, anticorps anon-WO0118547.84, anticorps dm-2MMP, anticorps dmmp2, anticorps l(2)02353, anticorps mmp2, anticorps wu:fa99h12, anticorps wu:fk89d01, anticorps fgmmp-2, anticorps Mmp-2, anticorps LOC100135793, anticorps Clg4a, anticorps GelA, anticorps MMP-2, anticorps CLG4, anticorps CLG4A, anticorps MMP-II, anticorps MONA, anticorps TBE-1, anticorps matrix metallopeptidase 2, anticorps Matrix metalloproteinase 2, anticorps matrix metalloproteinase 2, anticorps matrix metalloproteinase-2, anticorps MMP2, anticorps Mmp2, anticorps mmp2, anticorps LOC657982, anticorps LOC100135793

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 73882

ID gène: 4313

NCBI Accession: NP_001121363, NP_004521

UniProt: P08253

Pathways: Activation of Innate immune Response