IL36A/IL1F6 anticorps (AA 6-151)

N° du produit ABIN6654183

Détail du produit anti-IL36A/IL1F6 anticorps

Antigène: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Épitope: AA 6-151

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL36A/IL1F6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogène: Human IL-36 alpha recombinant protein (amino acids K6-D151) was used as the immunogen for the IL36A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the IL36A antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,ELISA (capture): 1-5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the IL36A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur IL36A/IL1F6

Antigène: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Autre désignation: IL-36 alpha / IL-1F6 (IL1F6 Produits)

Synonymes: anticorps Il1f6, anticorps Fil1, anticorps IL-1H1, anticorps IL1RP2, anticorps Il1f9, anticorps Il36a, anticorps FIL1, anticorps FIL1(EPSILON), anticorps FIL1E, anticorps IL-1F6, anticorps IL1(EPSILON), anticorps IL1F6, anticorps interleukin 36, alpha, anticorps interleukin 1 family, member 6 (epsilon), anticorps interleukin 1 family, member 6, anticorps interleukin 36 alpha, anticorps Il36a, anticorps IL1F6, anticorps IL36A, anticorps Il1f6

Sujet: Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene. The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.

UniProt: Q9UHA7

Pathways: Cancer Immune Checkpoints