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SPTA1 anticorps (AA 356-475)

SPTA1 Reactivité: Humain IHC (p), WB Hôte: Souris Monoclonal SCNA-1R unconjugated
N° du produit ABIN6654217
  • Antigène Tous les produits SPTA1
    SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
    Épitope
    AA 356-475
    Reactivité
    Humain
    Hôte
    • 2
    • 1
    Souris
    Clonalité
    • 3
    Monoclonal
    Conjugué
    • 3
    Cet anticorp SPTA1 est non-conjugé
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Purified
    Pureté
    Protein G affinity chromatography
    Immunogène
    A portion of amino acids 356-475 from the human protein was used as the immunogen for the recombinant SPTA1 antibody.
    Clone
    SCNA-1R
    Isotype
    IgG1 kappa
  • Indications d'application
    The stated application concentrations are suggested starting points. Titration of the recombinant SPTA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Western blot: 1-2 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
    Restrictions
    For Research Use only
  • Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Agent conservateur
    Azide free
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the recombinant SPTA1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène
    SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
    Autre désignation
    SPTA1 / Spectrin alpha 1 (SPTA1 Produits)
    Sujet
    This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [RefSeq]
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