Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

MECP2 anticorps (C-Term)

MECP2 Reactivité: Humain WB, ELISA, ChIP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6655271
  • Antigène Voir toutes MECP2 Anticorps
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Épitope
    • 19
    • 11
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 101
    • 40
    • 31
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 100
    • 7
    • 1
    Lapin
    Clonalité
    • 101
    • 7
    Polyclonal
    Conjugué
    • 62
    • 10
    • 8
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MECP2 est non-conjugé
    Application
    • 79
    • 63
    • 36
    • 30
    • 12
    • 10
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)
    Purification
    Anti-MeCP2 Antibody was purified by affinity purification. This product reacts with human MeCP2.  Cross reactivity with MeCP2 from species other than human is not known.
    Immunogène

    Immunogen: Anti-MeCP2 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing the C-terminal region of human MeCP2.

    Immunogen Type: Peptide

    Isotype
    IgG
    Top Product
    Discover our top product MECP2 Anticorps primaire
  • Indications d'application

    Application Note: Anti-MeCP2 Antibody is suitable for Chromatin Immunoprecipitation, ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 70 kDa in the appropriate cell lysate or extract.

    ChIP Dilution: 5 μg per IP

    ELISA Dilution: 1:1,000

    Western Blot Dilution: 1:1,000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

    0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300/p>

    Stabilizer: None

    Agent conservateur
    ProClin, Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Antigène
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Autre désignation
    MeCP2 (MECP2 Produits)
    Synonymes
    anticorps AUTSX3, anticorps MRX16, anticorps MRX79, anticorps MRXS13, anticorps MRXSL, anticorps PPMX, anticorps RS, anticorps RTS, anticorps RTT, anticorps 1500041B07Rik, anticorps BB130002, anticorps D630021H01Rik, anticorps Mbd5, anticorps WBP10, anticorps wu:fk96a04, anticorps zgc:111857, anticorps methyl-CpG binding protein 2, anticorps methyl CpG binding protein 2, anticorps methyl-CpG binding protein 2 S homeolog, anticorps MECP2, anticorps Mecp2, anticorps mecp2, anticorps mecp2.S
    Sujet

    Synonyms: Methyl-CpG-binding protein 2, MeCP-2 protein, AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT

    Background: MeCP2 is a chromosomal protein with abundant binding sites in the chromatin. It belongs to the family of methyl CpG binding proteins which also comprises MBD1, MBD2, MBD3 and MBD4. MeCP2 can bind specifically to methylated promoters, thereby repressing transcription. This transcriptional repression is mediated through interaction with histone deacetylase and the corepressor SIN3A. MeCP2 also is essential for development. Mutations in MeCP2 are the cause of several types of mental retardation including Rett syndrome, a progressive neurological disorder that causes mental retardation in females and mental retardation syndromic X-linked type 13, and may also be involved in Angelman syndrome and susceptibility to some types of autism. Anti-MeCP2 Antibody is ideal for research in Epigenetics, Embryonic Development and Neuroscience.

    Gene Name: MECP2

    ID gène
    4204
    NCBI Accession
    NP_001104262
    UniProt
    P51608
    Pathways
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
Vous êtes ici:
Support technique