CNTNAP2 anticorps (Extracellular Domain)

N° du produit ABIN6656679

Détail du produit anti-CNTNAP2 anticorps

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Épitope: Extracellular Domain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CNTNAP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-CASPR2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. No cross reactivity to CASPR/Paranodin. Cross-reactivity with CASPR2 from other sources has not been determined. Scaffolds research.

Immunogène:

Immunogen: CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2.

Immunogen Type: Recombinant Protein

Clone: S67-25

Isotype: IgG2a

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-CASPR2 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~180 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 1X PBS, pH 7.4

Stabilizer: 50 % (v/v) Glycerol

0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur CNTNAP2

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Autre désignation: CASPR2 (CNTNAP2 Produits)

Synonymes: anticorps AUTS15, anticorps CASPR2, anticorps CDFE, anticorps NRXN4, anticorps PTHSL1, anticorps 5430425M22Rik, anticorps Caspr2, anticorps mKIAA0868, anticorps CASPR, anticorps MGC145769, anticorps MGC147944, anticorps MGC147981, anticorps contactin associated protein like 2, anticorps contactin associated protein-like 2, anticorps contactin associated protein like 2b, anticorps CNTNAP2, anticorps Cntnap2, anticorps cntnap2b, anticorps cntnap2

Sujet:

Synonyms: Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868

Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.

Gene Name: CNTNAP2

ID gène: 26047

NCBI Accession: NP_054860

UniProt: Q9UHC6