ASCL2 anticorps (C-Term)

N° du produit ABIN6657882

Détail du produit anti-ASCL2 anticorps

Antigène: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Épitope: C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASCL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Réactivité croisée (Details): Cross reactivity with Ash2 from other species not tested.

Purification: Anti-Ash2 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Immunogène:

Immunogen: Anti-Ash2 Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Ash2: two containing an amino acid sequence from the internal and one containing an amino acid sequence from the C-terminal part of the protein.

Immunogen Type: Peptide

Information d'application

Indications d'application:

Application Note: Anti-Ash2 Antibody is suitable for ELISA, Immunofluorescence and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 68 kDa in the appropriate cell lysate or extract.

ELISA Dilution: 1:100 - 1:500

Western Blot Dilution: 1:1,000

IF Microscopy Dilution: 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

0.01 % (w/v) Sodium Azide

Stabilizer: None

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur ASCL2

Antigène: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Autre désignation: Ash2 (ASCL2 Produits)

Synonymes: anticorps ASH2, anticorps HASH2, anticorps MASH2, anticorps bHLHa45, anticorps ASCL2, anticorps 2410083I15Rik, anticorps Mash2, anticorps achaete-scute family bHLH transcription factor 2, anticorps ASCL2, anticorps Ascl2

Sujet:

Synonyms: Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L1, ASH2L2, Bre2

Background: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia. Anti-Ash2 Antibody is ideal for research in Gene Expression, Epigenetics, Cell Signaling and Cancer.

Gene Name: ASH2L

ID gène: 9070

NCBI Accession: NP_001098684

UniProt: Q9UBL3

Pathways: Stem Cell Maintenance