GRIA2 anticorps (C-Term)

N° du produit ABIN6658073

N° du produit (Fournisseur): 200-301-f34

Détail du produit anti-GRIA2 anticorps

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Épitope: C-Term

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

N° du produit (Fournisseur): 200-301-f34

Fournisseur: Rockland

Fonction: GluR2 Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with GluR2 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Purification: Anti-GluR2 Antibody was purified by Protein G chromatography.

Stérilité: Sterile filtered

Immunogène: GluR2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to a cytoplasmic C-terminus region of rat GluR2.

Clone: S21-32

Isotype: IgG1

Information d'application

Indications d'application:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1 μg/mL

Commentaires:

Anti-GluR2 Antibody is tested for use in WB and IHC, and is suitable in IP and Immuno-gold EM. Expect a band approximately ~90kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: GluR2 (GRIA2 Produits)

Sujet:

Synonyms: Glutamate receptor 2, GluR-2, GLUR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2

Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers. GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium.

Gene Name: GRIA2

ID gène: 29627

UniProt: P19491

Pathways: Signalisation PI3K-Akt