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GRIA2 anticorps (C-Term)

Rockland 200-301-f34 GRIA2 Reactivité: Rat WB, IHC, IP, FM Hôte: Souris Monoclonal S21-32 unconjugated
Rockland
N° du produit ABIN6658073
N° du produit (Fournisseur): 200-301-f34
  • Antigène Voir toutes GRIA2 Anticorps
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    Épitope
    • 29
    • 16
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 89
    • 64
    • 60
    • 13
    • 11
    • 11
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 87
    • 9
    Souris
    Clonalité
    • 75
    • 21
    Monoclonal
    Conjugué
    • 51
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp GRIA2 est non-conjugé
    Application
    • 78
    • 27
    • 27
    • 25
    • 23
    • 16
    • 16
    • 8
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
    N° du produit (Fournisseur)
    200-301-f34
    Fournisseur
    Rockland
    Fonction
    GluR2 Antibody
    Réactivité croisée (Details)
    A BLAST analysis was used to suggest cross-reactivity with GluR2 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.
    Purification
    Anti-GluR2 Antibody was purified by Protein G chromatography.
    Stérilité
    Sterile filtered
    Immunogène
    GluR2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to a cytoplasmic C-terminus region of rat GluR2.
    Clone
    S21-32
    Isotype
    IgG1
    Top Product
    Discover our top product GRIA2 Anticorps primaire
  • Indications d'application

    Immunoprecipitation_Dilution: User Optimized

    Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

    IF_Microscopy_Dilution: 1.0-10 μg/mL

    Western_Blot_Dilution: 1 μg/mL

    Commentaires

    Anti-GluR2 Antibody is tested for use in WB and IHC, and is suitable in IP and Immuno-gold EM. Expect a band approximately ~90kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Date de péremption
    12 months
  • Antigène
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    Autre désignation
    GluR2 (GRIA2 Produits)
    Sujet

    Synonyms: Glutamate receptor 2, GluR-2, GLUR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2

    Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers. GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium.

    Gene Name: GRIA2

    ID gène
    29627
    UniProt
    P19491
    Pathways
    Signalisation PI3K-Akt
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