CNTNAP1 anticorps

N° du produit ABIN6658098

Détail du produit anti-CNTNAP1 anticorps

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CNTNAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-CASPR Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASPR from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with CASPR from other sources has not been determined. Scaffolds research.

Immunogène:

Immunogen: CASPR Antibody was produced in mice by repeated immunizations with a fusion protein of rat CASPR.

Immunogen Type: Recombinant Protein

Clone: S65-35

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-CASPR Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~220 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur CNTNAP1

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Autre désignation: CASPR (CNTNAP1 Produits)

Synonymes: anticorps CNTNAP1, anticorps CASPR, anticorps CNTNAP, anticorps NRXN4, anticorps P190, anticorps Caspr, anticorps AI841080, anticorps NCP1, anticorps Nrxn4, anticorps p190, anticorps shm, anticorps contactin associated protein 1, anticorps contactin associated protein-like 1, anticorps CNTNAP1, anticorps cntnap1, anticorps Cntnap1

Sujet:

Synonyms: CASPR1, CNTP1, Contactin associated protein 1, NCP1, Paranodin, Neurexin 4, p190, CASPR, NRXN4

Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex. Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.

Gene Name: CNTNAP1

ID gène: 8506

NCBI Accession: NP_003623

UniProt: P78357

Pathways: Cell-Cell Junction Organization