HCN1 anticorps (C-Term)

N° du produit ABIN6658105

Détail du produit anti-HCN1 anticorps

Antigène: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Épitope: C-Term

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HCN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-HCN1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with HCN1 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against HCN2. Cross-reactivity with HCN1 from other sources has not been determined. Channels and Transporters research.

Immunogène:

Immunogen: HCN1 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to the C terminus region of rat HCN1.

Immunogen Type: Recombinant Protein

Clone: S70-28

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-HCN1 Antibody is suitable for use in WB, IP and IHC. Expect a band approximately ~100 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1-10 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur HCN1

Antigène: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Autre désignation: HCN1 (HCN1 Produits)

Synonymes: anticorps BCNG-1, anticorps BCNG1, anticorps HAC-2, anticorps Bcng1, anticorps C630013B14Rik, anticorps HAC2, anticorps hyperpolarization activated cyclic nucleotide gated potassium channel 1, anticorps hyperpolarization-activated cyclic nucleotide-gated potassium channel 1, anticorps hyperpolarization-activated, cyclic nucleotide-gated K+ 1, anticorps hcn1, anticorps HCN1, anticorps Hcn1

Sujet:

Synonyms: BCNG1, HAC2, potassium/sodium hyperpolarization activted cycli nucleotide gated channel 1

Background: Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulatons of cell excitability. Importantly, they contribute to spontaneous rhythmic activity in both the heart and brain.

Gene Name: Hcn1

ID gène: 84390

NCBI Accession: NP_445827

UniProt: Q9JKB0

Pathways: Asymmetric Protein Localization