KCNA1 anticorps (Extracellular Domain)
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- Antigène Voir toutes KCNA1 Anticorps
- KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
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Épitope
- Extracellular Domain
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Reactivité
- Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KCNA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
- Réactivité croisée
- Souris, Rat (Rattus)
- Purification
- Anti-Kv1.1 Extracellular Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv1.1 from Mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv1.1 from other sources has not been determined. Ion Channels research.
- Immunogène
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Immunogen: Kv1.1 Extracellular Antibody was produced in mice by repeated immunizations raised against a synthetic peptide at an extracellular domain of rat Kv1.1.
Immunogen Type: Peptide
- Clone
- S36-15
- Isotype
- IgG2b
- Top Product
- Discover our top product KCNA1 Anticorps primaire
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- Indications d'application
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-Kv1.1 Extracellular Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~56 kDa (could be 65-85 depending on glycosylation) on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Antigène
- KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
- Autre désignation
- Kv1.1 (KCNA1 Produits)
- Synonymes
- anticorps AEMK, anticorps EA1, anticorps HBK1, anticorps HUK1, anticorps KV1.1, anticorps MBK1, anticorps MK1, anticorps RBK1, anticorps KCNA1, anticorps AI840627, anticorps Kca1-1, anticorps Kv1.1, anticorps Mk-1, anticorps Shak, anticorps mceph, anticorps Kcna, anticorps Kcpvd, anticorps potassium voltage-gated channel subfamily A member 1, anticorps potassium voltage-gated channel, shaker-related subfamily, member 1, anticorps fragile site, aphidicolin type, common, fra(12)(q24), anticorps KCNA1, anticorps Kcna1, anticorps FRA12E
- Sujet
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Synonyms: KCA1, KCNA1, MBK1, MK1, RBK1, Shak, Voltage-gated potassium channel subunit Kv1.1, Potassium voltage gated channel subfamily A member 1, RBKI, RCK1
Background: Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene. It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.
Gene Name: Kcna1
- ID gène
- 24520
- NCBI Accession
- NP_775118
- UniProt
- P10499
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