Synaptojanin 1 anticorps (C-Term)
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- Antigène Voir toutes Synaptojanin 1 (SYNJ1) Anticorps
- Synaptojanin 1 (SYNJ1)
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Épitope
- C-Term
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Reactivité
- Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Synaptojanin 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Réactivité croisée (Details)
- Cross reactivity from other species has not been determined.
- Purification
- Anti-Synaptojanin 1 Monoclonal Antibody is directed against rat synaptojanin 1. Synaptojanin 1 antibody was Protein G purified. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.
- Immunogène
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Immunogen: Anti-Synaptojanin 1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant protein from the C-terminal region of rat synaptojanin 1.
Immunogen Type: Recombinant Protein
- Clone
- 5H1
- Isotype
- IgG
- Top Product
- Discover our top product SYNJ1 Anticorps primaire
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- Indications d'application
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Immunohistochemistry Dilution: 1:100
Application Note: Anti-Synaptojanin 1 antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 145 kDa in size corresponding to synaptojanin I proteins of rat brain extracts. Researchers should determine optimal titers for applications that are not stated below.
Western Blot Dilution: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- Antigène
- Synaptojanin 1 (SYNJ1)
- Autre désignation
- Synaptojanin 1 (SYNJ1 Produits)
- Synonymes
- anticorps CG6562, anticorps Dmel\\CG6562, anticorps IPP, anticorps Synj, anticorps fb02f11, anticorps fi15a11, anticorps nrc, anticorps wu:fb02f11, anticorps wu:fi15a11, anticorps SYNJ1, anticorps INPP5G, anticorps A930006D20Rik, anticorps AA675315, anticorps mKIAA0910, anticorps Synaptojanin, anticorps synaptojanin 1, anticorps Synj, anticorps synj1, anticorps SYNJ1, anticorps Synj1
- Sujet
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Synonyms: mouse anti-Synaptojanin 1 Antibody, Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1
Background: Synaptojanin 1 Monoclonal Antibody detects Synaptojanin 1, which is a phosphatidylinositol phosphatase involved in clathrin-mediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms, one that is ~ 145 kDA and is exclusively expressed in neurons, and the other ~ 170 kDa which is expressed in non-neuronal, peripheral tissues. The gene which encodes Synaptojanin 1, SYNJ1, has been mapped to chromosome 21 thus making it a candidate for involvement in Down's syndrome (DS). It has recently been demonstrated that Ts65Dn mice (the most commonly used model of DS) have altered phosphatidylinositol-4,5-bisphosphate metabolism. This defect is rescued by restoring SYNJ1 to disomy in the Ts65Dn mice.
Gene Name: SYNJ1
- ID gène
- 85238
- UniProt
- Q62910
- Pathways
- Inositol Metabolic Process, Synaptic Vesicle Exocytosis
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