MMP7 anticorps (AA 151-250)
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- Antigène Voir toutes MMP7 Anticorps
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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Épitope
- AA 151-250
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MMP7 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from mouse MMP7
- Isotype
- IgG
- Top Product
- Discover our top product MMP7 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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Biocompatibility of Intensified Decellularized Equine Carotid Arteries in a Rat Subcutaneous Implantation Model and in a Human In Vitro Model." dans: Tissue engineering. Part A, (2017) (PubMed).
: "TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma." dans: American journal of cancer research, Vol. 5, Issue 10, pp. 3030-41, (2015) (PubMed).
: "Activating transcription factor 4 promotes esophageal squamous cell carcinoma invasion and metastasis in mice and is associated with poor prognosis in human patients." dans: PLoS ONE, Vol. 9, Issue 7, pp. e103882, (2014) (PubMed).
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Biocompatibility of Intensified Decellularized Equine Carotid Arteries in a Rat Subcutaneous Implantation Model and in a Human In Vitro Model." dans: Tissue engineering. Part A, (2017) (PubMed).
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- Antigène
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
- Autre désignation
- MMP-7 (MMP7 Produits)
- Synonymes
- anticorps MAT, anticorps MPMM, anticorps MMP-7, anticorps MPSL1, anticorps PUMP-1, anticorps matrilysin, anticorps LOC727698, anticorps MMP7, anticorps Matrilysin, anticorps matrix metallopeptidase 7, anticorps MMP7, anticorps Mmp7
- Sujet
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Synonyms: Matrilysin, Matrilysin uterine, Matrin, Matrix Metalloproteinase 7, MMP 7, MMP7, MPSL1, PUMP 1, Pump 1 protease, PUMP1, Uterine Matrilysin, Uterine metalloproteinase.
Background: Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28kD proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18kD active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, hepatocellular carcinomas, rectal carcinomas, and approximately 50 % of gliomas.
- Pathways
- Production of Molecular Mediator of Immune Response
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