WNK4 anticorps (Cy3)
-
- Antigène Voir toutes WNK4 Anticorps
- WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp WNK4 est conjugé à/à la Cy3
-
Application
- Western Blotting (WB)
- Réactivité croisée
- Souris
- Homologie
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human WNK4
- Isotype
- IgG
- Top Product
- Discover our top product WNK4 Anticorps primaire
-
-
- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
- Autre désignation
- WNK4 (WNK4 Produits)
- Synonymes
- anticorps WNK4, anticorps PHA2B, anticorps PRKWNK4, anticorps 2010002J11Rik, anticorps Pha2b, anticorps Prkwnk4, anticorps Ac2-059, anticorps WNK lysine deficient protein kinase 4, anticorps WNK4, anticorps Wnk4
- Sujet
-
Synonyms: PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, WNK lysine deficient protein kinase 4, WNK4_HUMAN.
Background: Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Also inhibits the renal K(+)channel, KCNJ1, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis.
- ID gène
- 65266
-