Muscarinic Acetylcholine Receptor M2 anticorps (AA 168-250)

N° du produit ABIN668646

Détail du produit anti-Muscarinic Acetylcholine Receptor M2 anticorps

Antigène: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Épitope: AA 168-250

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Muscarinic Acetylcholine Receptor M2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ChRM2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Muscarinic Acetylcholine Receptor M2 (ABIN668646)

Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." dans: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).

Détails sur Muscarinic Acetylcholine Receptor M2

Antigène: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Autre désignation: ChRM2 (CHRM2 Produits)

Synonymes: anticorps HM2, anticorps AChR-M2, anticorps Chrm-2, anticorps M2, anticorps chrm2, anticorps Acm2, anticorps GPM2, anticorps cholinergic receptor muscarinic 2, anticorps cholinergic receptor, muscarinic 2, cardiac, anticorps cholinergic receptor, muscarinic 2a, anticorps cholinergic receptor, muscarinic 2, anticorps CHRM2, anticorps Chrm2, anticorps chrm2a

Sujet:

Synonyms: HM2, Muscarinic acetylcholine receptor M2, CHRM2

Background: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3), this then triggers calcium ion release into the cytosol.

ID gène: 1129

UniProt: P08172