Thyroperoxidase anticorps (AA 351-450)

N° du produit ABIN668736

Détail du produit anti-Thyroperoxidase anticorps

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Épitope: AA 351-450

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thyroperoxidase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse Thyroid peroxidase

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Thyroperoxidase

Antigène: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Autre désignation: Thyroid peroxidase (TPO Produits)

Synonymes: anticorps MSA, anticorps TDH2A, anticorps TPX, anticorps TPO, anticorps msa, anticorps tpx, anticorps xtpo, anticorps LOC100218312, anticorps thyroid peroxidase, anticorps TPO, anticorps Tpo, anticorps tpo, anticorps LOC100547103

Sujet:

Synonyms: Thyroid peroxidase, TPO

Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].

ID gène: 22018

UniProt: P35419

Pathways: Thyroid Hormone Synthesis