SLC1A5 anticorps (AA 465-515)

N° du produit ABIN669081

Détail du produit anti-SLC1A5 anticorps

Antigène: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Épitope: AA 465-515

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC1A5 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLC1A5

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SLC1A5 (ABIN669081)

Díaz-Carballo, Klein, Acikelli, Wilk, Saka, Jastrow, Wennemuth, Dammann, Giger-Pabst, Khosrawipour, Rassow, Nienen, Strumberg: "Cytotoxic stress induces transfer of mitochondria-associated human endogenous retroviral RNA and proteins between cancer cells." dans: Oncotarget, Vol. 8, Issue 56, pp. 95945-95964, (2017) (PubMed).

Huang, Zhao, Zhao, Wu, Jiang, Ma, Zhang: "Upregulated SLC1A5 promotes cell growth and survival in colorectal cancer." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 6006-14, (2014) (PubMed).

Détails sur SLC1A5

Antigène: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Autre désignation: SLC1A5 (SLC1A5 Produits)

Synonymes: anticorps aaat, anticorps asct2, anticorps atbo, anticorps m7v1, anticorps m7vs1, anticorps r16, anticorps rdrc, anticorps AAAT, anticorps ASCT2, anticorps ATBO, anticorps M7V1, anticorps M7VS1, anticorps R16, anticorps RDRC, anticorps Slc1a7, anticorps Asct2, anticorps H4-ASCT2, anticorps solute carrier family 1 (neutral amino acid transporter), member 5, anticorps solute carrier family 1 member 5 S homeolog, anticorps solute carrier family 1 member 5, anticorps slc1a5, anticorps slc1a5.S, anticorps SLC1A5, anticorps Slc1a5

Sujet:

Synonyms: R16, AAAT, ATBO, M7V1, RDRC, ASCT2, M7VS1, Neutral amino acid transporter B(0), ATB(0), Baboon M7 virus receptor, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5, SLC1A5, RDR

Background: Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).

ID gène: 6510

UniProt: Q15758

Pathways: Dicarboxylic Acid Transport, L'effet Warburg