Adiponectin Receptor 2 anticorps (AA 315-340)

N° du produit ABIN670851

Détail du produit anti-Adiponectin Receptor 2 anticorps

Antigène: Adiponectin Receptor 2 (ADIPOR2)

Épitope: AA 315-340

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adiponectin Receptor 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody may cross react with Adiponectin receptor 1 due to sequence similarity.

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Adiponectin receptor 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Adiponectin Receptor 2 (ABIN670851)

Morad, Abrahamsson, Dabrosin: "Estradiol affects extracellular leptin:adiponectin ratio in human breast tissue in vivo." dans: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. 3460-7, (2014) (PubMed).

Ji, Wu, Ma, Ma, Qin: "The effect of resveratrol on the expression of AdipoR1 in kidneys of diabetic nephropathy." dans: Molecular biology reports, Vol. 41, Issue 4, pp. 2151-9, (2014) (PubMed).

Guo, Qin, Zhang, Li, Yin: "Effect of rosiglitazone on the expression of cardiac adiponectin receptors and NADPH oxidase in type 2 diabetic rats." dans: European journal of pharmacology, Vol. 685, Issue 1-3, pp. 116-25, (2012) (PubMed).

Liu, Wu, Zhang, Chen, Liu, Wu, Zhu: "The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats." dans: European journal of pharmacology, Vol. 650, Issue 1, pp. 384-9, (2010) (PubMed).

Détails sur Adiponectin Receptor 2

Antigène: Adiponectin Receptor 2 (ADIPOR2)

Autre désignation: Adiponectin receptor 2 (ADIPOR2 Produits)

Synonymes: anticorps MGC84736, anticorps ADIPOR2, anticorps paqr2, anticorps acdcr2, anticorps LOC100220214, anticorps ACDCR2, anticorps PAQR2, anticorps 1110001I14Rik, anticorps ADCR2, anticorps AI115388, anticorps AW554121, anticorps D6Ucla1e, anticorps Paqr2, anticorps si:ch211-281k12.9, anticorps zgc:136273, anticorps adiponectin receptor 2 L homeolog, anticorps adiponectin receptor 2, anticorps adipor2.L, anticorps ADIPOR2, anticorps adipor2, anticorps Adipor2

Sujet:

Synonyms: PAQR2, ACDCR2, Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2

Background: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.

ID gène: 79602

UniProt: Q86V24

Pathways: AMPK Signaling