MRP1 anticorps (AA 501-600)

N° du produit ABIN671526

Détail du produit anti-MRP1 anticorps

Antigène: MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))

Épitope: AA 501-600

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse MRP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-MRP1 (ABIN671526)

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Yan, Xie, Li, Zhang, Ma, Xie, Li, Zhong: "Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, (2013) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Détails sur MRP1

Antigène: MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))

Autre désignation: MRP1 (MRP1 Produits)

Synonymes: anticorps Abcc1a, anticorps Avcc1a, anticorps Mrp, anticorps Mrp1, anticorps BTCC-1, anticorps DRAP-27, anticorps MIC3, anticorps MRP-1, anticorps TSPAN-29, anticorps TSPAN29, anticorps Scya6, anticorps c10, anticorps ATP binding cassette subfamily C member 1, anticorps CD9 molecule, anticorps chemokine (C-C motif) ligand 6, anticorps Abcc1, anticorps CD9, anticorps Ccl6

Sujet:

Synonyms: MRP, Mrp1, Mdrap, Abcc1a, Abcc1b, Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, LTC4 transporter, Abcc1

Background: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

ID gène: 17250

UniProt: O35379

Pathways: Response to Water Deprivation, Cell-Cell Junction Organization