C-JUN anticorps (AA 31-331)

N° du produit ABIN671691

Détail du produit anti-C-JUN anticorps

Highlights:

• High quality C-JUN Anticorps primaire for the detection of JUN.
• Reliable product with high standard validation data

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Épitope: AA 31-331

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C-JUN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Poulet, Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human c-Jun

Isotype: IgG

Informations sur le produit:

What can the C-JUN Antibody ABIN671691 be used for?: This polyclonal C-JUN Antibody detects C-JUN. The C-JUN Antibody has been validated for various applications and can be used for the detection of C-JUN and derivatives by Western Blotting, ELISA, Immunohistochemistry (Paraffin-embedded Sections), Flow Cytometry, Immunofluorescence (Cultured Cells), Immunofluorescence (Paraffin-embedded Sections), Immunohistochemistry (Frozen Sections).

What validation data is available for this C-JUN Antibody?: The Anticorps primaire is referenced in 5 publications and is characterized by a proven, very high reliability. It has currently 6 product images that show its performance in a variety of applications. The product is currently available in 100 μL quantity. C-JUN Antibody for the detection of C-JUN and derivatives.

What is the function of C-JUN?: This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008].

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-C-JUN (ABIN671691)

Liu, Lv, Ning, Yang, Zhu: "Therapeutic effects of 1,25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model." dans: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2284-2292, (2016) (PubMed).

Zhou, Lu, Wang, Xiao, Liu, Xing: "microRNA let-7c is essential for the anisomycin-elicited apoptosis in Jurkat T cells by linking JNK1/2 to AP-1/STAT1/STAT3 signaling." dans: Scientific reports, Vol. 6, pp. 24434, (2016) (PubMed).

Zhang, Lin, Jin, Lin, Cao, Zheng: "Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway." dans: Oncology reports, Vol. 36, Issue 1, pp. 23-30, (2016) (PubMed).

Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." dans: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).

Zhang, Pan, Xu, Niu, Ma, Xu: "Interleukin 18 augments growth ability via NF-?B and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells." dans: Gene, Vol. 563, Issue 1, pp. 45-51, (2015) (PubMed).

Détails sur C-JUN

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Autre désignation: c-Jun (JUN Produits)

Synonymes: anticorps AP-1, anticorps AP1, anticorps c-Jun, anticorps fj36h07, anticorps wu:fj36h07, anticorps zgc:65863, anticorps Junc, anticorps c-jun, anticorps CG2275, anticorps D-Jun, anticorps D-jun, anticorps D-jun/Jra, anticorps DJUN, anticorps DJun, anticorps Djun, anticorps Dmel\\CG2275, anticorps JRA, anticorps JUN, anticorps Jun, anticorps V, anticorps cJun, anticorps d-JRA, anticorps d-Jun, anticorps d-jun, anticorps dAP-1, anticorps dJRA, anticorps dJUN, anticorps dJra, anticorps dJun, anticorps djun, anticorps dm-Jun, anticorps jra, anticorps jun, anticorps l(2)46Ef, anticorps l(2)IA109, anticorps l(2R)IA109, anticorps Jun proto-oncogene, AP-1 transcription factor subunit, anticorps jun proto-oncogene S homeolog, anticorps jun proto-oncogene, anticorps Jun-related antigen, anticorps jun proto-oncogene L homeolog, anticorps JUN, anticorps Jun, anticorps jun.S, anticorps jun, anticorps Jra, anticorps jun.L

Sujet:

Synonyms: AP1, AP-1, c-Jun, Transcription factor AP-1, Activator protein 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

ID gène: 3725

UniProt: P05412

Pathways: Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins