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BCL9L anticorps (AA 397-666)

BCL9L Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6719451
  • Antigène Voir toutes BCL9L Anticorps
    BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
    Épitope
    • 13
    • 10
    • 7
    • 1
    • 1
    • 1
    AA 397-666
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 26
    • 1
    Lapin
    Clonalité
    • 26
    • 1
    Polyclonal
    Conjugué
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BCL9L est non-conjugé
    Application
    • 20
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for BCL9L detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for BCL9L detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human BCL9L recombinant protein (Position: E397-A666).
    Isotype
    IgG
    Top Product
    Discover our top product BCL9L Anticorps primaire
  • Indications d'application

    Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

    Commentaires

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
    Autre désignation
    BCL9L (BCL9L Produits)
    Synonymes
    anticorps BCL9-2, anticorps DLNB11, anticorps B9L, anticorps BC003321, anticorps bcl9-2, anticorps BCL9L, anticorps B-cell CLL/lymphoma 9 like, anticorps B cell CLL/lymphoma 9-like, anticorps B-cell CLL/lymphoma 9-like, anticorps BCL9L, anticorps Bcl9l, anticorps bcl9l
    Sujet

    Synonyms: B-cell CLL/lymphoma 9-like protein, B-cell lymphoma 9-like protein, BCL9-like protein, Protein BCL9-2, BCL9L, DLNB11

    Background: B-cell CLL/lymphoma 9 like is a protein that in humans is encoded by the BCL9L gene. It is mapped to 11q23.3. Bcl-9 (B-cell lymphoma 9, also Protein legless homolog) is a transcriptional regulator that belongs to the Bcl-9 family of proteins. It is expressed in multiple tissues and serves to recruit Pygopus to the Wnt-pathway beta -catenin-TCF complex in the nucleus. Bcl-9 and Bcl-9-2 are considered evolutionary duplicates of Legless that perform the same task with different regulation. Human Bcl-9 is 1426 amino acids (aa) in length. It contains one phosphothreonine and three phosphoserine sites that have been identified so far, two poly-Pro regions (aa 514-517 and 970-973), and one poly-Ala segment (aa 900-903). There is one potential alternate start site at Met27, and a variant isoform exists that shows a four aa substitution for aa 1391-1426. Over aa 1009-1328, human Bcl-9 is 96 % aa identical to mouse Bcl-9.

    ID gène
    283149
    Pathways
    Stem Cell Maintenance
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