SCRIB anticorps (AA 172-409)

N° du produit ABIN7354662

Détail du produit anti-SCRIB anticorps

Antigène: SCRIB (Scribbled Homolog (SCRIB))

Épitope: AA 172-409

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCRIB est non-conjugé

Application: Flow Cytometry (FACS)

Fonction: Rabbit IgG Polyclonal Anti-Human SCRIBBLE Antibody DyLight® 550 Conjugated, Flow Validated.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG Polyclonal Anti-Human SCRIBBLE Antibody DyLight® 550 Conjugated, Flow Validated.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human SCRIBBLE recombinant protein (Position: F172-K409).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Flow Cytometry|1-3 μg/1x106 cells

Commentaires:

Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: At 2-8°C for one year. Protect from light. Do not freeze.

Détails sur SCRIB

Antigène: SCRIB (Scribbled Homolog (SCRIB))

Autre désignation: SCRIB (SCRIB Produits)

Sujet:

Synonyms: Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL

Background: SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.

ID gène: 23513

UniProt: Q14160

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization