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BIRC7 anticorps (AA 101-200)

BIRC7 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN672561
  • Antigène Voir toutes BIRC7 Anticorps
    BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
    Épitope
    • 14
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 63
    • 14
    • 14
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 55
    • 7
    • 1
    Lapin
    Clonalité
    • 56
    • 7
    Polyclonal
    Conjugué
    • 33
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BIRC7 est non-conjugé
    Application
    • 50
    • 19
    • 16
    • 12
    • 12
    • 12
    • 10
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Livin
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Faruk, Ibrahim, Aminu, Adamu, Abdullahi, Suleiman, Rafindadi, Mohammed, Iliyasu, Idoko, Saidu, Randawa, Musa, Ntekim, Shah, Abubakar, Adoke, Manko, Awasum: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." dans: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).

    Zhang, Peng, Luo, Zhou: "Prospective experimental studies on the renal protective effect of ulinastatin after paraquat poisoning." dans: World journal of emergency medicine, Vol. 3, Issue 4, pp. 299-304, (2014) (PubMed).

  • Antigène
    BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
    Autre désignation
    Livin (BIRC7 Produits)
    Synonymes
    anticorps KIAP, anticorps LIVIN, anticorps ML-IAP, anticorps MLIAP, anticorps RNF50, anticorps EIAP/XLX, anticorps XLX, anticorps kiap, anticorps livin, anticorps ml-iap, anticorps mliap, anticorps rnf50, anticorps xEIAP, anticorps RGD1562883, anticorps zgc:165605, anticorps E130019N06, anticorps Livin, anticorps birc7, anticorps bird7a, anticorps xEIAP/XLX, anticorps xlx, anticorps EIAP/XLX-B, anticorps birc7b, anticorps baculoviral IAP repeat containing 7, anticorps baculoviral IAP repeat-containing 7, anticorps baculoviral IAP repeat-containing 7 (livin), anticorps baculoviral IAP repeat containing 7 S homeolog, anticorps baculoviral IAP repeat containing 7 L homeolog, anticorps BIRC7, anticorps birc7, anticorps Birc7, anticorps birc7.S, anticorps birc7.L
    Sujet

    Synonyms: KIAP, LIVIN, MLIAP, RNF50, ML-IAP, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, RING finger protein 50, BIRC7, UNQ5800/PRO19607/PRO21344

    Background: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.

    ID gène
    79444
    UniProt
    Q96CA5
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