Macrophage Mannose Receptor 1 anticorps (FITC)
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- Antigène Voir toutes Macrophage Mannose Receptor 1 (MRC1) Anticorps
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Macrophage Mannose Receptor 1 est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
- Clone
- C068C2
- Isotype
- IgG2a, kappa
- Top Product
- Discover our top product MRC1 Anticorps primaire
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- Indications d'application
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
- Commentaires
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Matching Isotype Control: FITC Rat IgG2a, κ Isotype Control (ABIN7469839)
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Antigène
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- Autre désignation
- CD206 (MRC1 Produits)
- Synonymes
- anticorps CD206, anticorps CLEC13D, anticorps CLEC13DL, anticorps MMR, anticorps MRC1L1, anticorps bA541I19.1, anticorps AW259686, anticorps MR, anticorps mrc1, anticorps MGC86525, anticorps MRC1, anticorps MRC1L-A, anticorps mannose receptor C-type 1, anticorps mannose receptor, C type 1, anticorps mannose receptor C-type 1 L homeolog, anticorps mediator of replication checkpoint 1, anticorps MRC1, anticorps Mrc1, anticorps mrc1.L, anticorps mrc1
- Sujet
- MMR,MR,MRC1,macrophage mannose receptor,mannose receptor,CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
- ID gène
- 17533
- UniProt
- Q61830
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