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CD3 anticorps (mFluor™450)

GMP Grade CD3 Reactivité: Humain FACS Hôte: Souris Monoclonal UCHT1 mFluor™450
N° du produit ABIN6731073
  • Antigène Voir toutes CD3 Anticorps
    CD3
    Reactivité
    • 216
    • 106
    • 34
    • 20
    • 18
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    Humain
    Hôte
    • 264
    • 55
    • 20
    • 13
    • 8
    Souris
    Clonalité
    • 350
    • 6
    Monoclonal
    Conjugué
    • 104
    • 44
    • 36
    • 28
    • 25
    • 13
    • 10
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD3 est conjugé à/à la mFluor™450
    Application
    • 311
    • 99
    • 64
    • 63
    • 46
    • 44
    • 43
    • 24
    • 18
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Fonction
    CD3 mFluor™ 450 Antibody
    Attributs du produit
    The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.
    Purification
    Purified
    Pureté
    >95 %
    Classe de qualité
    GMP Grade
    Immunogène
    Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
    Clone
    UCHT1
    Isotype
    IgG1, kappa
    Top Product
    Discover our top product CD3 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    2-8°C, Conjugated antibodies should never be frozen.
  • Antigène
    CD3
    Autre désignation
    CD3 (CD3 Produits)
    Synonymes
    anticorps CD3, anticorps AI504783, anticorps CD3epsilon, anticorps T3e, anticorps cd3-gamma, anticorps cd3g, anticorps cd3g-a, anticorps cd3g/d, anticorps cd3gd, anticorps t3g, anticorps CD3e molecule, anticorps CD3d molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps CD3g molecule S homeolog, anticorps CD3E, anticorps CD3D, anticorps Cd3e, anticorps cd3g.S
    ID gène
    916
    NCBI Accession
    NM_000733
    UniProt
    P07766
    Pathways
    TCR Signaling, Ubiquitin Proteasome Pathway
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