Aggrecan anticorps (AA 101-220)

N° du produit ABIN673599

Détail du produit anti-Aggrecan anticorps

Antigène: Aggrecan (ACAN)

Épitope: AA 101-220

Reactivité: Humain, Rat, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aggrecan est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Lapin, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Aggrecan core protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Aggrecan (ABIN673599)

Hu, Yang, Chen, Sun, Lin, Yang: "Optimization of puncture injury to rat caudal disc for mimicking early degeneration of intervertebral disc." dans: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2017) (PubMed).

Zhao, Hao, Wang, Wang: "Effect of Choline on the Composition and Degradation Enzyme of Extracellular Matrix of Mice Chondrocytes Exposed to Fluoride." dans: Biological trace element research, (2016) (PubMed).

Liu, Yu, Ma, Xiang, Hu, Chen: "Lentivirus-mediated TGF-β3, CTGF and TIMP1 gene transduction as a gene therapy for intervertebral disc degeneration in an in vivo rabbit model." dans: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1399-1404, (2016) (PubMed).

Shi, Ma, Zhang, Li, Jiang, Qin: "Hypoxia combined with spheroid culture improves cartilage specific function in chondrocytes." dans: Integrative biology : quantitative biosciences from nano to macro, (2015) (PubMed).

Lei, Li, Li, Gao, Chen, Jin: "Mesenchymal stem cell characteristics of dental pulp and periodontal ligament stem cells after in vivo transplantation." dans: Biomaterials, Vol. 35, Issue 24, pp. 6332-43, (2014) (PubMed).

Ren, Liu, Ma, Liu, Diao, Yang, Zhang, Xi, Hu: "Treatment of rabbit intervertebral disc degeneration with co-transfection by adeno-associated virus-mediated SOX9 and osteogenic protein-1 double genes in vivo." dans: International journal of molecular medicine, Vol. 32, Issue 5, pp. 1063-8, (2014) (PubMed).

Détails sur Aggrecan

Antigène: Aggrecan (ACAN)

Autre désignation: Aggrecan core protein 1 (ACAN Produits)

Synonymes: anticorps AGC1, anticorps AGCAN, anticorps CSPG1, anticorps CSPGCP, anticorps MSK16, anticorps SEDK, anticorps Agc, anticorps Agc1, anticorps Cspg1, anticorps b2b183Clo, anticorps cmd, anticorps aggrecan, anticorps aggrecan core protein, anticorps ACAN, anticorps Acan, anticorps LOC100380783, anticorps AGC

Sujet:

Synonyms: AGC1, SEDK, AGCAN, CSPG1, MSK16, CSPGCP, Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, ACAN

Background: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

ID gène: 176

UniProt: P16112

Pathways: Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport