IRGC anticorps (AA 73-122)

N° du produit ABIN6746505

Détail du produit anti-IRGC anticorps

Antigène: IRGC (Immunity-Related GTPase Family, Cinema (IRGC))

Épitope: AA 73-122

Reactivité: Humain, Rat, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRGC est non-conjugé

Application: Western Blotting (WB)

Specificité: Mouse IRGC

Homologie: Percent identity by BLAST analysis: Mouse (100%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide located between aa73-122 of mouse Irgc1 (Q8C262, NP_950178). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Elephant, Panda, Dog (100%), Galago, Marmoset, Bovine, Bat, Horse, Pig, Guinea pig (92%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Références pour anticorps anti-IRGC (ABIN6746505)

Bolton, Anthony, Perry: "Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo." dans: Neuroscience, Vol. 86, Issue 4, pp. 1245-57, (1998) (PubMed).

Fanning, Jameson, Jesaitis, Anderson: "The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton." dans: The Journal of biological chemistry, Vol. 273, Issue 45, pp. 29745-53, (1998) (PubMed).

Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: "Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues." dans: The Journal of cell biology, Vol. 133, Issue 1, pp. 43-7, (1996) (PubMed).

Détails sur IRGC

Antigène: IRGC (Immunity-Related GTPase Family, Cinema (IRGC))

Autre désignation: IRGC1 / CINEMA (IRGC Produits)

Sujet: Name/Gene ID: IRGC

Synonyms: IRGC, CINEMA, Iigp5, IFGGE, Interferon inducible GTPase 5, IRGC1, Interferon-inducible GTPase 5, R30953_1

ID gène: 56269

NCBI Accession: NP_950178

UniProt: Q6NXR0