Kallikrein 9 anticorps (AA 51-150) (Biotin)

N° du produit ABIN676045

Détail du produit anti-Kallikrein 9 anticorps (Biotin)

Antigène: Kallikrein 9 (KLK9)

Épitope: AA 51-150

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 9 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KLK9

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Kallikrein 9

Antigène: Kallikrein 9 (KLK9)

Autre désignation: KLK9 (KLK9 Produits)

Synonymes: anticorps KLK-L3, anticorps KLKL3, anticorps 1200016C12Rik, anticorps AI324041, anticorps Klk9, anticorps Klks3, anticorps rGK-9, anticorps rK9, anticorps kallikrein related peptidase 9, anticorps kallikrein related-peptidase 9, anticorps kallikrein 1-related peptidase C9, anticorps KLK9, anticorps Klk9, anticorps Klk1c9

Sujet:

Synonyms: Kallikrein 8, Kallikrein 9, Kallikrein L3, Kallikrein Like 3, Kallikrein like protein 3, kallikrein related peptidase 9, Kallikrein-9, Kallikrein-like protein 3, Kallikrein8, Kallikrein9, KLK 8, KLK 9, KLK L3, KLK-L3, KLK8, KLK9, KLK9_HUMAN, KLKL 3, KLKL3.

Background: Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.

ID gène: 284366

Pathways: Système du Complément