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ITGAV/ITGB1 anticorps

ITGAV/ITGB1 Reactivité: Humain, Souris, Rat WB, FACS, IF (cc), ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN676718
  • Antigène Tous les produits ITGAV/ITGB1
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    Reactivité
    • 18
    • 18
    • 18
    • 3
    • 3
    • 3
    Humain, Souris, Rat
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGAV/ITGB1 est non-conjugé
    Application
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Hendesi, Barbe, Safadi, Monroy, Popoff: "Integrin mediated adhesion of osteoblasts to connective tissue growth factor (CTGF/CCN2) induces cytoskeleton reorganization and cell differentiation." dans: PLoS ONE, Vol. 10, Issue 2, pp. e0115325, (2015) (PubMed).

  • Antigène
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    Autre désignation
    Integrin Alpha V + Beta 1 (ITGAV/ITGB1 Produits)
    Sujet

    Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

    Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).

    ID gène
    3685, 3688
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