NOS2 anticorps (AA 14-100)

N° du produit ABIN677228

Détail du produit anti-NOS2 anticorps

Antigène: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Épitope: AA 14-100

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Poulet, Humain, Souris, Rat

Homologie: Dog,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse NOS-2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-NOS2 (ABIN677228)

Liu, Li, Yang, Niu, Zhao, Zhao, Wang: "Valproic acid attenuates inflammation of optic nerve and apoptosis of retinal ganglion cells in a rat model of optic neuritis." dans: Biomedicine & pharmacotherapy, Vol. 96, pp. 1363-1370, (2018) (PubMed).

Zhao, Jiang, Wang, Geng, Wang, Han, Wang: "The Roles of Reactive Oxygen Species and Nitric Oxide in Perfluorooctanoic Acid-Induced Developmental Cardiotoxicity and l-Carnitine Mediated Protection." dans: International journal of molecular sciences, Vol. 18, Issue 6, (2017) (PubMed).

Sun, Yang, Zhang, Zhao: "Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats." dans: Experimental animals, (2017) (PubMed).

Xiong, Wang, Chu, Chen, Guo: "Salvianolic Acid B Restored Impaired Barrier Function via Downregulation of MLCK by microRNA-1 in Rat Colitis Model." dans: Frontiers in pharmacology, Vol. 7, pp. 134, (2016) (PubMed).

Bai, Zhang, Li, Liu, Lou, Ma, Luo, Ren: "Somatostatin prevents lipopolysaccharide?induced neurodegeneration in the rat substantia nigra by inhibiting the activation of microglia." dans: Molecular medicine reports, Vol. 12, Issue 1, pp. 1002-8, (2015) (PubMed).

Sun, Zhang, Guan, Zhou, Sun: "Alpha-lipoic acid attenuates trinitrobenzene sulfonic acid-induced ulcerative colitis in mice." dans: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 358-67, (2015) (PubMed).

Wang, Fang, Hu, Li, Hong: "Seawater immersion aggravates sciatic nerve injury in rats." dans: Experimental and therapeutic medicine, Vol. 9, Issue 4, pp. 1153-1160, (2015) (PubMed).

Pei, Wang et al.: "Propofol attenuates LPS-induced tumor necrosis factor-?, interleukin-6 and nitric oxide expression in canine peripheral blood mononuclear cells possibly through down-regulation of nuclear factor ..." dans: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, (2014) (PubMed).

Karadeniz, Cavuso?lu, Turkmen, Uyan?kgil, Karadeniz, Akdemir, Tuglu, Ates, Erbas: "Experimental comparison of protective characteristics of enalapril and trimetazidine in diabetic nephropathy." dans: Renal failure, Vol. 36, Issue 8, pp. 1283-90, (2014) (PubMed).

Détails sur NOS2

Antigène: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Autre désignation: iNOS (NOS2 Produits)

Synonymes: anticorps HEP-NOS, anticorps INOS, anticorps NOS, anticorps NOS2A, anticorps NOS-II, anticorps Nos-2, anticorps Nos2a, anticorps i-NOS, anticorps iNOS, anticorps iNos, anticorps NOS2a, anticorps NOS2, anticorps BmNOS2, anticorps Nsl, anticorps nos2, anticorps nitric oxide synthase 2, anticorps nitric oxide synthase 2, inducible, anticorps inducible nitric oxide synthase, anticorps inducible nitric-oxide synthase, anticorps nanos C2HC-type zinc finger 2, anticorps NOS2, anticorps Nos2, anticorps nos2, anticorps LOC396821, anticorps NANOS2

Sujet:

Synonyms: iNOS, Nos-2, Nos2a, i-NOS, NOS-II, Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, Macrophage NOS, MAC-NOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Nos2, Inosl

Background: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

ID gène: 18126

UniProt: P29477

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process