ADAR anticorps (AA 1001-1226)

N° du produit ABIN678233

Détail du produit anti-ADAR anticorps

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Épitope: AA 1001-1226

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ADAR1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ADAR

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Autre désignation: ADAR1 (ADAR Produits)

Synonymes: anticorps red1, anticorps drada, anticorps wu:fc22a02, anticorps adar1, anticorps dsRAD, anticorps dsRAD-1, anticorps ADAR, anticorps ADAR1, anticorps CG12598, anticorps Dmel\\CG12598, anticorps EG:BACN35H14.1, anticorps adar, anticorps adr, anticorps cg12598, anticorps dADAR, anticorps dAdar, anticorps hypnos-2, anticorps NV18763, anticorps AGS6, anticorps DRADA, anticorps DSH, anticorps DSRAD, anticorps G1P1, anticorps IFI-4, anticorps IFI4, anticorps K88DSRBP, anticorps P136, anticorps AV242451, anticorps Adar1, anticorps mZaADAR, anticorps adenosine deaminase, RNA-specific, anticorps adenosine deaminase, RNA-specific S homeolog, anticorps adenosine deaminase, RNA specific, anticorps Adenosine deaminase acting on RNA, anticorps adenosine deaminase acting on RNA, anticorps double-stranded RNA-specific editase 1, anticorps adar, anticorps adar.S, anticorps ADAR, anticorps Adar, anticorps CpipJ_CPIJ011849, anticorps LOC100114127

Sujet:

Synonyms: 136 kDa double stranded RNA binding protein, Adar 1, ADAR, Adar1, Adenosine deaminase RNA specic 1, Adenosine deaminase RNA specic, Adenosine deaminase that act on RNA, AV242451, Double stranded RNA specic adenosine deaminase, Double-stranded RNA-specic editase Adar, Drada, Dsh, Dsrad, dsRNA adenosine deaminase, EC 3.5.4.-, G1P1, I 4, I4, i4 protein, Interferon induced protein 4, Interferon inducible protein 4, K88dsrbp, mZaADAR, p136, Pre-mRNA adenosine deaminase, RNA adenosine deaminase 1, RNA-editing deaminase 1, RNA-editing enzyme 1.

Background: ADAR1 converts adenosine to inosine in dsRNA, which destabilizes the dsRNA helix. This activity is important for various functions like site-specific RNA editing of transcripts of the glutamate receptors and modifying viral RNA genomes (which may be responsible for hypermutation of certain negative-stranded viruses, e.g., measles virus). ADAR1 also binds to short interfering RNAs (siRNA) without editing them and suppresses siRNA-mediated RNA interference. This protein is ubiquitously expressed, with the highest levels being found in brain and lung.

ID gène: 103

Pathways: Protein targeting to Nucleus