CD51 anticorps (AA 51-150)

N° du produit ABIN678983

Détail du produit anti-CD51 anticorps

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Épitope: AA 51-150

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD51 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Integrin alpha V

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CD51 (ABIN678983)

Agarwal, Loder, Sorkin, Li, Shrestha, Zhao, Mishina, James, Levi: "Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification." dans: Stem cells (Dayton, Ohio), Vol. 34, Issue 6, pp. 1692-701, (2016) (PubMed).

Ulmasov, Neuschwander-Tetri, Lai, Monastyrskiy, Bhat, Yates, Oliva, Prinsen, Ruminski, Griggs: "Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice." dans: Cellular and molecular gastroenterology and hepatology, Vol. 2, Issue 4, pp. 499-518, (2016) (PubMed).

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: Integrin alpha V/CD51 (ITGAV Produits)

Synonymes: anticorps 1110004F14Rik, anticorps 2610028E01Rik, anticorps CD51, anticorps D430040G12Rik, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps Cd51, anticorps integrin subunit alpha V, anticorps integrin alpha V, anticorps ITGAV, anticorps Itgav

Sujet:

Synonyms: CD51, MSK8, VNRA, VTNR, Integrin alpha-V, Vitronectin receptor subunit alpha, ITGAV

Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

ID gène: 3685

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex