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NOTCH2 anticorps (AA 1501-1700)

NOTCH2 Reactivité: Humain, Souris WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN680183
  • Antigène Voir toutes NOTCH2 Anticorps
    NOTCH2 (Notch 2 (NOTCH2))
    Épitope
    • 16
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1501-1700
    Reactivité
    • 68
    • 51
    • 30
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 74
    • 6
    • 3
    • 3
    • 1
    Lapin
    Clonalité
    • 73
    • 11
    • 2
    Polyclonal
    Conjugué
    • 39
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOTCH2 est non-conjugé
    Application
    • 47
    • 29
    • 25
    • 25
    • 21
    • 13
    • 11
    • 10
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Notch2
    Isotype
    IgG
    Top Product
    Discover our top product NOTCH2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NOTCH2 (Notch 2 (NOTCH2))
    Autre désignation
    Notch 2 (NOTCH2 Produits)
    Synonymes
    anticorps AGS2, anticorps HJCYS, anticorps hN2, anticorps AI853703, anticorps N2, anticorps notch6, anticorps sb:cb884, anticorps neurogenic locus notch homolog protein 2, anticorps notch 2, anticorps notch 3, anticorps LOC581186, anticorps NOTCH2, anticorps notch3, anticorps Notch2, anticorps notch2
    Sujet

    Synonyms: hN2, AGS2, HJCYS, Neurogenic locus notch homolog protein 2, Notch 2, NOTCH2

    Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation.

    ID gène
    4853
    UniProt
    Q04721
    Pathways
    Signalisation Notch, Stem Cell Maintenance
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