CD161 anticorps (AA 151-225) (Biotin)
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- Antigène Voir toutes CD161 (KLRB1) Anticorps
- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
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Épitope
- AA 151-225
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD161 est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CD161/NK11
- Isotype
- IgG
- Top Product
- Discover our top product KLRB1 Anticorps primaire
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- Indications d'application
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
- Autre désignation
- CD161 (KLRB1 Produits)
- Synonymes
- anticorps NKR-P1, anticorps KLRB1, anticorps 4930431A04Rik, anticorps Gm4696, anticorps Klrb1g, anticorps Klrb6, anticorps Ly-55, anticorps Ly55, anticorps NKR-P1G, anticorps Nkrp-1e, anticorps Nkrp1g, anticorps CD161, anticorps CLEC5B, anticorps NKR, anticorps NKR-P1A, anticorps NKRP1A, anticorps hNKR-P1A, anticorps Klrb1d, anticorps Klrb1f, anticorps Nkr-p1e, anticorps killer cell lectin like receptor B1, anticorps killer cell lectin-like receptor subfamily B member 1, anticorps killer cell lectin-like receptor subfamily B, member 1, anticorps KLRB1, anticorps Klrb1
- Sujet
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Synonyms: NKR, CD161, CLEC5B, NKR-P1, NKRP1A, NKR-P1A, hNKR-P1A, Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, Natural killer cell surface protein P1A, KLRB1
Background: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
- ID gène
- 3820
- UniProt
- Q12918
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