DIRAS3 anticorps (AA 131-229)

N° du produit ABIN681448

Détail du produit anti-DIRAS3 anticorps

Antigène: DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))

Épitope: AA 131-229

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIRAS3 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ARHI

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DIRAS3

Antigène: DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))

Autre désignation: ARHI (DIRAS3 Produits)

Synonymes: anticorps DIRAS3, anticorps arhi, anticorps noey2, anticorps ARHI, anticorps NOEY2, anticorps DIRAS family GTPase 3, anticorps DIRAS family GTP binding RAS like 3, anticorps DIRAS3, anticorps diras3

Sujet:

Synonyms: ARHI, NOEY2, GTP-binding protein Di-Ras3, Distinct subgroup of the Ras family member 3, Rho-related GTP-binding protein RhoI, DIRAS3, RHOI

Background: ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane localization motif. ARHI mRNA is detected in all normal breast and ovarian epithelial cell cultures tested, as well as in normal ovary, heart, liver, pancreas and brain however ARHI expression is down-regulated in breast and ovarian tumors. Reactivation of ARHI expression in breast cancer cells is associated with increased histone H3 acetylation and decreased lysine 9 methylation of histone H3.

ID gène: 9077

UniProt: O95661