PARD3 anticorps (AA 1201-1356)

N° du produit ABIN681718

Détail du produit anti-PARD3 anticorps

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Épitope: AA 1201-1356

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PARD-3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PARD3

Antigène: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Autre désignation: PARD-3 (PARD3 Produits)

Synonymes: anticorps ASIP, anticorps Baz, anticorps PAR3, anticorps PAR3alpha, anticorps PARD-3, anticorps PARD3A, anticorps SE2-5L16, anticorps SE2-5LT1, anticorps SE2-5T2, anticorps Par3, anticorps AA960621, anticorps AI256638, anticorps D8Ertd580e, anticorps PAR-3, anticorps Pard3a, anticorps asip, anticorps bazooka, anticorps par-3, anticorps par3, anticorps pard3, anticorps par-3 family cell polarity regulator, anticorps partitioning defective 3 homolog, anticorps par-3 family cell polarity regulator alpha, b, anticorps par-3 family cell polarity regulator S homeolog, anticorps PARD3, anticorps Pard3, anticorps LOC100551156, anticorps LOC100473914, anticorps pard3, anticorps pard3ab, anticorps pard3.S

Sujet:

Synonyms: Baz, ASIP, PAR3, PARD-3, PARD3A, SE2-5T2, PPP1R118, SE2-5L16, SE2-5LT1, PAR3alpha, Partitioning defective 3 homolog, PAR-3, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3A

Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.

ID gène: 56288

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization