MAP3K11 anticorps (AA 355-460) (Cy3)
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- Antigène Voir toutes MAP3K11 Anticorps
- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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Épitope
- AA 355-460
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAP3K11 est conjugé à/à la Cy3
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificité
- Due to the similarity of this protein to MLK1 2 and 4, there is a chance that this antibody will cross-react based on homology.
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Cow,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MLK3
- Isotype
- IgG
- Top Product
- Discover our top product MAP3K11 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
- Autre désignation
- MLK3 (MAP3K11 Produits)
- Synonymes
- anticorps MEKK11, anticorps MLK-3, anticorps MLK3, anticorps PTK1, anticorps SPRK, anticorps 2610017K16Rik, anticorps Mlk3, anticorps Mlk-3, anticorps RHOE, anticorps mitogen-activated protein kinase kinase kinase 11, anticorps MAP3K11, anticorps Map3k11
- Sujet
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Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11
Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
- Poids moléculaire
- 94kDa
- ID gène
- 4296
- UniProt
- Q16584
- Pathways
- Signalisation MAPK, Interferon-gamma Pathway
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