ARFIP2 anticorps (pSer260)

N° du produit ABIN682783

Détail du produit anti-ARFIP2 anticorps

Antigène: ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))

Épitope: pSer260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARFIP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human arfaptin 2 around the phosphorylation site of Ser260

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ARFIP2

Antigène: ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))

Autre désignation: arfaptin 2 (ARFIP2 Produits)

Synonymes: anticorps POR1, anticorps 2310002N04Rik, anticorps POR, anticorps Por1, anticorps ARFIP2, anticorps im:7136059, anticorps zgc:112066, anticorps ADP ribosylation factor interacting protein 2, anticorps ADP-ribosylation factor interacting protein 2, anticorps ADP-ribosylation factor interacting protein 2b, anticorps ARFIP2, anticorps Arfip2, anticorps arfip2b

Sujet:

Synonyms: ADP ribosylation factor interacting protein 2, Arfaptin 2, ARFIP2, Partner of RAC1, POR1, ARFP2_HUMAN.

Background: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

ID gène: 23647