FANCD2 anticorps (pSer222)

N° du produit ABIN682918

Détail du produit anti-FANCD2 anticorps

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Épitope: pSer222

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser222

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FANCD2

Antigène: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Autre désignation: FANCD2 (FANCD2 Produits)

Synonymes: anticorps FANCD2, anticorps CG17269, anticorps CG31192, anticorps CG31194, anticorps Dmel\\CG17269, anticorps dmFANCD2, anticorps xfancd2, anticorps FA-D2, anticorps FA4, anticorps FACD, anticorps FAD, anticorps FAD2, anticorps FANCD, anticorps 2410150O07Rik, anticorps AU015151, anticorps BB137857, anticorps Fanconi anemia complementation group D2, anticorps CG17269 gene product from transcript CG17269-RA, anticorps Fanconi anemia group D2 protein, anticorps Fanconi anemia, complementation group D2, anticorps Fanconi anemia complementation group D2 L homeolog, anticorps FANCD2, anticorps Fancd2, anticorps LOC100455970, anticorps fancd2, anticorps fancd2.L

Sujet:

Synonyms: FANCD2 phospho S222, FANCD2 phospho Ser222, p-FANCD2 phospho S222, FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2.

Background: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

ID gène: 2177

Pathways: Réparation de l'ADN