Afadin anticorps (pSer1721)

N° du produit ABIN683713

Cet anticorps Lapin Polyclonal détecte spécifiquement Afadin dans ELISA, WB, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Afadin anticorps (pSer1721) (ABIN683713)

Antigène: Afadin (MLLT4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Afadin est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Afadin anticorps

Épitope: pSer1721

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Afadin around the phosphorylation site of Ser1721 [VL(p-S)PD]

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Afadin

Antigène: Afadin (MLLT4)

Autre désignation: Afadin

Sujet:

Synonyms: p-AfadinSer1721, Afadin phospho S1721, Afadin phospho Ser1721, MLLT4, Protein AF6, AF6, Afadin, AFAD_HUMAN, ALL1-fused gene from chromosome 6 protein, Protein AF-6.

Background: Afadin is a cell-cell adherens junction F-actin binding multidomain protein. Two splice variants of afadin have been described: l-afadin, which is ubiquitously expressed, and the smaller s-afadin, which is abundantly expressed in neural tissue. l-Afadin contains one PDZ domain near its middle followed by three proline-rich and one F-actin-binding region at the carboxyl-terminal. l/s-Afadin is localized to cell-cell junctions and binds several cytoplasmic proteins such as the small GTPase Ras, the tight junction protein ZO-1, and the vinculin binding protein ponsin/SH3P12.

ID gène: 4301

Pathways: Cell-Cell Junction Organization