Afadin anticorps (pSer1721)

N° du produit ABIN683713

Détail du produit anti-Afadin anticorps

Antigène: Afadin (MLLT4)

Épitope: pSer1721

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Afadin est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Afadin around the phosphorylation site of Ser1721 [VL(p-S)PD]

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Afadin

Antigène: Afadin (MLLT4)

Autre désignation: Afadin (MLLT4 Produits)

Synonymes: anticorps MLLT4, anticorps af-6, anticorps af6, anticorps si:ch211-278j12.1, anticorps AF6, anticorps RP3-431P23.3, anticorps 5033403D15Rik, anticorps Af-6, anticorps Afadin, anticorps Gm314, anticorps I-afadin, anticorps S-afadin, anticorps Af6, anticorps afadin, adherens junction formation factor, anticorps afadin, adherens junction formation factor L homeolog, anticorps afadin, adherens junction formation factor a, anticorps afadin, anticorps AFDN, anticorps afdn.L, anticorps afdna, anticorps LOC589923, anticorps LOC100177180, anticorps afdn, anticorps Afdn

Sujet:

Synonyms: p-AfadinSer1721, Afadin phospho S1721, Afadin phospho Ser1721, MLLT4, Protein AF6, AF6, Afadin, AFAD_HUMAN, ALL1-fused gene from chromosome 6 protein, Protein AF-6.

Background: Afadin is a cell-cell adherens junction F-actin binding multidomain protein. Two splice variants of afadin have been described: l-afadin, which is ubiquitously expressed, and the smaller s-afadin, which is abundantly expressed in neural tissue. l-Afadin contains one PDZ domain near its middle followed by three proline-rich and one F-actin-binding region at the carboxyl-terminal. l/s-Afadin is localized to cell-cell junctions and binds several cytoplasmic proteins such as the small GTPase Ras, the tight junction protein ZO-1, and the vinculin binding protein ponsin/SH3P12.

ID gène: 4301

Pathways: Cell-Cell Junction Organization