TANK anticorps (AA 151-260) (Cy3)
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- Antigène Voir toutes TANK Anticorps
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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Épitope
- AA 151-260
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TANK est conjugé à/à la Cy3
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human TANK
- Isotype
- IgG
- Top Product
- Discover our top product TANK Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Autre désignation
- TANK (TANK Produits)
- Synonymes
- anticorps I-TRAF, anticorps ITRAF, anticorps TRAF2, anticorps C86182, anticorps E430026L09Rik, anticorps zgc:153048, anticorps i-traf, anticorps tank, anticorps traf2, anticorps TRAF family member associated NFKB activator, anticorps TRAF family member-associated Nf-kappa B activator, anticorps TRAF family member-associated NFKB activator, anticorps TRAF family member associated NFKB activator L homeolog, anticorps TANK, anticorps Tank, anticorps tank, anticorps tank.L
- Sujet
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Synonyms: I TRAF, ITRAF, TRAF family member associated NF KAPPA B activator, TRAF family member associated NFKB activator, TRAF interacting protein, TRAF interacting protein TANK isoform a, I-TRAF, Tank, TANK_HUMAN, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, TRAF interacting protein TANK isoform b, TRAF2.
Background: TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, this protein can block TRAF2 binding to LMP1, the Epstein Barr virus transforming protein, and inhibit LMP1-mediated NF kappa B activation.
- ID gène
- 10010
- Pathways
- Signalisation p53, Signalisation TLR, Activation of Innate immune Response
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