ATG4B anticorps (AA 85-200)

N° du produit ABIN685777

Détail du produit anti-ATG4B anticorps

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Épitope: AA 85-200

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ATG4B

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B (ATG4B Produits)

Synonymes: anticorps apg4b, anticorps APG4B, anticorps AUTL1, anticorps 2510009N07Rik, anticorps AW048066, anticorps Apg4b, anticorps Atg4bl, anticorps Autl1, anticorps Aut2b2, anticorps autophagy related 4B cysteine peptidase, anticorps autophagy-related 4b, anticorps Peptidase family C54 protein, anticorps cysteine protease ATG4B, anticorps ATG4 autophagy related 4 homolog B (S. cerevisiae), anticorps autophagy related 4B, cysteine peptidase, anticorps autophagy related 4B, cysteine peptidase L homeolog, anticorps ATG4B, anticorps Atg4b, anticorps AT3G59950, anticorps Tsp_08582, anticorps Tsp_11599, anticorps atg4b, anticorps atg4b.L

Sujet:

Synonyms: APG4B, AUTL1, Cysteine protease ATG4B, AUT-like 1 cysteine endopeptidase, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, hAPG4B, ATG4B, KIAA0943

Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

ID gène: 23192

UniProt: Q9Y4P1

Pathways: Autophagy