KLF6 anticorps

N° du produit ABIN685927

Détail du produit anti-KLF6 anticorps

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KLF6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur KLF6

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Autre désignation: Klf6/Pac1 (KLF6 Produits)

Sujet:

Synonyms: Kruppel-like factor 6, B cell derived protein 1, BCD1, COPEB, Core promoter element-binding protein, CPBP, GC rich sites binding factor GBF, Krueppel-like factor 6, Proto-oncogene BCD1, Transcription factor Zf9, Zf9, CBA1, DKFZp686N0199, GBF, PAC1, ST12, KLF6_HUMAN.

Background: KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.

ID gène: 1316