CD130/gp130 anticorps (AA 651-750)
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- Antigène Voir toutes CD130/gp130 (IL6ST) Anticorps
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
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Épitope
- AA 651-750
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD130/gp130 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from mouse IL6R beta
- Isotype
- IgG
- Top Product
- Discover our top product IL6ST Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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Interleukin‑6 induces an epithelial‑mesenchymal transition phenotype in human adamantinomatous craniopharyngioma cells and promotes tumor cell migration." dans: Molecular medicine reports, Vol. 15, Issue 6, pp. 4123-4131, (2018) (PubMed).
: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." dans: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, (2017) (PubMed).
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Interleukin‑6 induces an epithelial‑mesenchymal transition phenotype in human adamantinomatous craniopharyngioma cells and promotes tumor cell migration." dans: Molecular medicine reports, Vol. 15, Issue 6, pp. 4123-4131, (2018) (PubMed).
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- Antigène
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- Autre désignation
- IL-6R Beta/CD130/gp130 (IL6ST Produits)
- Synonymes
- anticorps CD130, anticorps CDW130, anticorps GP130, anticorps IL-6RB, anticorps 5133400A03Rik, anticorps AA389424, anticorps BB405851, anticorps D13Ertd699e, anticorps gp130, anticorps Ac1055, anticorps Gp130, anticorps Il-6rb, anticorps IL-6, anticorps interleukin 6 signal transducer, anticorps IL6ST, anticorps Il6st, anticorps il6st
- Sujet
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Synonyms: Interleukin-6 receptor subunit beta, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130, gp130, Oncostatin-M receptor subunit alpha, CD130, Il6st
Background: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development.
- ID gène
- 16195
- UniProt
- Q00560
- Pathways
- Signalistation JAK/STAT, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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