IL23R anticorps (AA 401-550)

N° du produit ABIN686857

Détail du produit anti-IL23R anticorps

Antigène: IL23R (Interleukin 23 Receptor (IL23R))

Épitope: AA 401-550

Reactivité: Humain, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL23R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Chien, Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IL-23R

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IL23R (ABIN686857)

Wang, Zhong, Zheng, Li, Chen, Ma, Sun, Yan, Li: "Damage effect of interleukin (IL)-23 on oxygen-glucose-deprived cells of the neurovascular unit via IL-23 receptor." dans: Neuroscience, Vol. 289C, pp. 406-416, (2015) (PubMed).

Détails sur IL23R

Antigène: IL23R (Interleukin 23 Receptor (IL23R))

Autre désignation: IL-23R (IL23R Produits)

Synonymes: anticorps IL-23R, anticorps IL23R, anticorps il-23r, anticorps interleukin 23 receptor, anticorps IL23R, anticorps il23r, anticorps Il23r

Sujet:

Synonyms: Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R

Background: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

ID gène: 149233

UniProt: Q5VWK5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation