ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) (AA 1051-1280) anticorps (Cy7)
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- Antigène Voir toutes ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Anticorps
- ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)
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Épitope
- AA 1051-1280
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cy7
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MDR1
- Isotype
- IgG
- Top Product
- Discover our top product ABCB1B Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)
- Autre désignation
- MDR1 (ABCB1B Produits)
- Synonymes
- anticorps ABC20, anticorps CD243, anticorps CLCS, anticorps GP170, anticorps MDR1, anticorps P-GP, anticorps PGY1, anticorps Abcb1, anticorps Mdr1, anticorps Mdr1b, anticorps Pgy-1, anticorps Pgy1, anticorps mdr, anticorps ATP binding cassette subfamily B member 1, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 1B, anticorps ATP-binding cassette, subfamily B (MDR/TAP), member 1B, anticorps ABCB1, anticorps Abcb1b
- Sujet
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Synonyms: P-Glycoprotein, Multi Drug Resistance Associated Protein, ABCB1, ATP-binding cassette sub-family B MDR/TAP, member 1, ABC20, CD243, CD243 antigen, CLCS, Multidrug resistance protein 1, P glycoprotein 1, p-GP, gp170, P gp, PGY1.
Background: P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.
- ID gène
- 5243
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