BIRC6 anticorps (AA 4701-4857)

N° du produit ABIN687292

Détail du produit anti-BIRC6 anticorps

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Épitope: AA 4701-4857

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC6 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Apollon

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur BIRC6

Antigène: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Autre désignation: Apollon/BIRC6 (BIRC6 Produits)

Synonymes: anticorps APOLLON, anticorps BRUCE, anticorps bruce, anticorps apollon, anticorps BIRC6, anticorps A430032G04Rik, anticorps A430040A19Rik, anticorps AA501170, anticorps Bruce, anticorps D630005A10Rik, anticorps mKIAA1289, anticorps baculoviral IAP repeat containing 6, anticorps baculoviral IAP repeat-containing 6, anticorps BIRC6, anticorps Birc6, anticorps birc6

Sujet:

Synonyms: BRUCE, APOLLON, Baculoviral IAP repeat-containing protein 6, BIR repeat-containing ubiquitin-conjugating enzyme, Ubiquitin-conjugating BIR domain enzyme apollon, BIRC6, KIAA1289

Background: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.

ID gène: 57448

UniProt: Q9NR09