CD46 anticorps (AA 251-355)
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- Antigène Voir toutes CD46 Anticorps
- CD46
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Épitope
- AA 251-355
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD46 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from Mouse CD46
- Isotype
- IgG
- Top Product
- Discover our top product CD46 Anticorps primaire
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anti-CD46 (CD46) (AA 35-179) antibody
CD46 Reactivité: Humain FACS, ELISA, IHC Hôte: Souris Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 40-320) antibodyCD46 Reactivité: Humain WB, IF, IHC Hôte: Lapin Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 Reactivité: Humain WB, FACS, ELISA, IF, IHC Hôte: Lapin Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 Reactivité: Humain, Boeuf (Vache) WB, FACS, IP Hôte: Souris Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 Reactivité: Humain, Boeuf (Vache) WB, FACS, IP Hôte: Souris Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 Reactivité: Humain WB, FACS, IF, IHC (p) Hôte: Lapin Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibody (FITC)CD46 Reactivité: Humain, Boeuf (Vache) FACS Hôte: Souris Monoclonal MEM-258 FITC
anti-CD46 (CD46) antibody (Biotin)CD46 Reactivité: Humain, Boeuf (Vache) WB, FACS, IP Hôte: Souris Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibodyCD46 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Monoclonal 7D12 unconjugated Recombinant Antibody
anti-CD46 (CD46) antibody (APC)CD46 Reactivité: Humain, Boeuf (Vache) FACS Hôte: Souris Monoclonal MEM-258 APC
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CD46
- Autre désignation
- CD46/MCP (CD46 Produits)
- Synonymes
- anticorps AHUS2, anticorps MCP, anticorps MIC10, anticorps TLX, anticorps TRA2.10, anticorps Mcp, anticorps CD46, anticorps CD46 molecule, anticorps CD46 antigen, complement regulatory protein, anticorps CD46 molecule, complement regulatory protein, anticorps membrane cofactor protein-like, anticorps CD46, anticorps Cd46, anticorps LOC100341359, anticorps LOC103789310
- Sujet
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Synonyms: MCP, TLX, AHUS2, MIC10, TRA2.10, Membrane cofactor protein, Trophoblast leukocyte common antigen, CD46
Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
- ID gène
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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